Other than the obvious problems mentioned, you have to make sure that the tire itsef is wide enough for the rim. A 10 inch rim probably wants a 300mm tire in order to seal properly. I haven't dabbled with that for years now, but when I was in high school and we were looking to run the widest tires possible, I know some people bought rims that were so wide that the tires didn't fit properly and they were hard to get the bead to pop into place. More often though people would want to run a wide tire on a narrow rim, which also caused a problem.